Determination of cadmium by ion chromatography using 10-(2-pyridylazo)-9-phenanthrol as a postcolumn derivatization reagent.

Determination of bovine blood oleandrin by high-performance liquid chromatography and postcolumn derivatization.

A high-performance liquid chromatographic procedure with a postcolumn fluorescence derivatization is developed for the analysis of oleandrin in bovine blood. Oleandrin is separated by an octadecylsilane-bonded column with a mobile phase containing dehydroascorbic acid. The effluent of the column is mixed with concentrated hydrochloric acid and passed through poly(tetrafluoroethylene) tubing mai...

Determination of dialkyldiselenides in water by gas chromatography-mass spectrometry using 1-fluoro-2,4-dinitrobenzene as derivatization reagent.

The feasibility of gas chromatography-mass spectrometry for the speciation of traces of dialkyldiselenides in the presence of dialkylselenides and inorganic selenium species is described, and the procedure is applied to environmental samples. The analysis is based on the reaction of dialkyldiselenide species with 1-fluoro-2,4-dinitrobenzene after volatilization of selenium species as alkylselen...

Determination of N-Methylpyrrolidine in Cefepime Using a Reagent-Free Ion Chromatography System

Determination of Sulfate and Sulfamate in Topiramate Using a Reagent-Free Ion Chromatography System

Introduction Epilepsy is a common neurological disorder that can cause anywhere from a brief cessation of responsiveness to severe muscle spasms with a loss of consciousness.1 This condition is usually controlled with antiepileptic drugs (AEDs). However, approximately 20% of patients with epilepsy are resistant to therapy with first-generation AEDs.2 Topiramate (Topamax®) is a second-generation...

Determination of 9, 10-phenanthrenequinone in airborne particulates by High-Performance Liquid Chromatography with post-column fluorescence derivatization using 2-aminothiophenol.

9, 10-Phenanthrenequinone (PQ) is regarded as a harmful environmental pollutant and its presence has been reported in atmospheric environment. The measurement of PQ in environment should be necessary to evaluate the influence of PQ on human health. We found that PQ reacted with 2-aminothiophenol under acidic condition to form fluorescent derivative which emits green fluorescence at 510nm. Based...